Translational Bioinformatics Scientist – Neurosciences

Job title:

Translational Bioinformatics Scientist – Neurosciences

Company

UCB

Job description

Make your mark for patientsWe are looking for a creative and highly driven Translational Bioinformatics Scientist – Neurosciences to join our team based in Braine l’Alleud, Belgium.About the roleYou will be part of a highly motivated, multi-disciplinary global team passionate about improving our understanding of the molecular mechanisms that drive complex, chronic diseases and response to treatment. We strive to increase the predictability of drug discovery and development and bring differentiated therapies to those living with severe diseases.Who you’ll work withYou will interact with lab scientists, function and project leaders, helping them design data rich experiments to answer biological questions and share and discuss results of data analyses. You will evolve in a vibrant and enriching scientific environment, be exposed to academic collaborations and ambitious drug discovery projects across our three research sites, and benefit from the cumulative experience of a global bioinformatics team.What you’ll doThe successful applicant will help assist UCB’s therapeutic ambitions in epilepsy, neurodegeneration and neuroinflammation by unlocking mechanistic insights from transcriptomic and metabolomic profiling of patient samples, analysing perturbations of patient-derived cell systems and in vivo / ex vivo animal models, and enriching our knowledge of disease aetiology to inform new targets and drug mechanism of action.Interested? For this role we’re looking for the following education, experience and skillsCandidates must be at least PhD level in biology/bioinformatics/computer science with experience in the following areas:

• Strong understanding of neurosciences and molecular mechanisms of disease enabling interpretation of results
• Demonstrated experience in data-driven target discovery and biological mechanism elucidation
• Thoroughly versed with statistical concepts, data mining, analysis and visualization of biological data types acquired through hands-on experience, including programming in R and/or Python
• A good understanding of RNA- and DNAseq analysis best practices (single-cell, spatial, epigenomics, etc).
• Ability to utilise a diverse toolbox of methods for biological interpretation of gene expression data including pathway analysis, functional module detection, and causal reasoning will be a distinct advantage
• Good understanding of recent advances of generative and predictive AI applied to biology understanding and target prioritization is a must, with operational knowledge of major AI frameworks considered a plus.
• Published experience of analysis and interpretation of alterations in gene expression in neurological conditions is an advantage

Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!About us
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.Why work with us?
At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on EMEA-Reasonable_Accommodation@ucb.com. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.

Expected salary

Location

Eigenbrakel, Waals Brabant

Job date

Fri, 21 Feb 2025 08:22:49 GMT

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