Senior Scientist Molecular Pharmaceutics

Job title:

Senior Scientist Molecular Pharmaceutics

Company

Johnson & Johnson

Job description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.comJob Function: Discovery & Pre-Clinical/Clinical DevelopmentJob Sub Function: Pharmaceutical Product R&DJob Category: Scientific/TechnologyAll Job Posting Locations: BE009 Turnhoutseweg 30Job Description:About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at https://www.jnj.com/innovative-medicinePharmaceutical & Material Sciences is, within the Pharmaceutical Development & Supply (PPDS) organization of the Pharmaceutical Companies of Johnson and Johnson, responsible for high-throughput experimentation, preformulation, biopharmaceutics, solid state form selection and understanding, and material selection and qualification.In Belgium (Beerse) there is a vacancy for a Senior/Principal Scientist Molecular Pharmaceutics.Within this role you will provide expert scientific advice to drive mechanistic understanding of drug delivery.The overall mission of the position is to work together with a team of experts in molecular design, solid form design and formulation design and provide in silico support to select, develop and understand the behavior of Active Pharmaceutical Ingredients, functional excipients, and drug formulations in each phase of development. The role is related to the development of synthetic molecules, with a specific focus on oral peptide delivery.You will be responsible for:Conduct simulations using modeling techniques such as molecular dynamics to investigate the behavior and interactions of the active pharmaceutical ingredients and functional excipients in drug products and physiological environments.Translate scientific insights into molecular and formulation design strategies starting from the early development stage throughout the entire product development lifecycle.Troubleshoot fundamental challenges associated with the physicochemical properties of the compound, drug product, as well as excipients.Drive innovation in computational flows and approaches to support new drug delivery modalities with focus on the oral delivery of macromolecules.Liaise with experimental analytical and formulation scientists to contextualize the relevance of modeling in product development.Take part in research collaborations with academic and private organizations and consortia.Work in a multidisciplinary team of researchers, internally as well as externally building and maintaining a strong relationship with key stakeholders.Qualifications / Requirements:Ph.D. or Master’s degree in Physical or Computational Chemistry, Biophysics, Pharmaceutical Sciences, Chemical Engineering, Materials Science, or a related field with 3+ years of experience focussing on molecular dynamics or computer simulations.Proficiency in molecular modeling applications in drug development (e.g. GROMACS, AMBER, DL_POLY and commercial software like Schrodinger, Biovia …) and scripting languages (e.g., bash, Python, R…).Experience with working in a High-Performance Computing environment.Insights into the broader pharmaceutical product development picture and understanding of biopharmaceutics and physicochemical principles and their impact on molecular and formulation design is considered an advantage.Team player, dynamic, creative, innovative and flexible.

Expected salary

Location

Beerse, Antwerpen

Job date

Thu, 27 Mar 2025 04:16:40 GMT

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