Principal Scientist Protein Biochemistry – Expression Systems Lab Head

GlaxoSmithKline

Job title:

Principal Scientist Protein Biochemistry – Expression Systems Lab Head

Company

GlaxoSmithKline

Job description

Job PurposeProtein Biochemistry group has a mission to design and generate vaccine candidates by understanding their relation to disease using state-of-the art technology and talent, ensuring delivery of best-in-class vaccines to the patients.Your roleThe Expert Scientist in Protein Biochemistry group is expected to lead, design and execute scientific studies in support to vaccine projects or technological platforms in discovery, development or life cycle management. More specifically, he will be the reference in the team for early vaccine candidate production using prokaryotic/eukaryotic expression systems, molecular virology technologies or molecular bacteriology technologies.Key Responsibilities

  • Leads the development and implementation of innovative expression system technologies for recombinant proteins and ensures alignment and state of the art for a given technology across the department.
  • Responsible for the conception, design, implementation, and interpretation of scientific research experiments in support of vaccine development
  • Performs data management and draws conclusions from experimental data. Based on data interpretation suggests next steps to meet project objectives.
  • Supervises and leads a team of scientist(s) and/or technician(s) ensuring clear and effective communication, task allocation, and performance monitoring.
  • Active participation and presentation of lab results in internal meetings, working groups and technical and project team meetings, ensuring quality interpretation and extensive quality check of raw data.
  • Ensures highest ethical standards, good scientific practices & data integrity are implemented in daily scientific activities.
  • Ensures timely data collection, & reporting (including participation to internal/external scientific documents) in area of responsibility.
  • Demonstrates knowledge of the key research activities and basic regulations
  • Takes appropriate actions to resolve issues in area of responsibility affecting research strategy and progress.
  • Can advise Discovery project and Vaccine development leaders on scientific issues related to their projects, notably through participation at project team or technical team meetings.
  • Can supervise collaborative research studies with third parties but also PhD students or postdoc.
  • Can be the principal author of publications submitted to peer review journals.

Why you?Basic Qualifications:We are looking for professionals with these required skills to achieve our goals:

  • PhD in Life Sciences with +3 years of postdoctoral experience, or Master’s degree with 6+ years of experience in pharmaceutical industry.
  • In depth understanding and hands-on experience using state-of-the-art expression system technologies (eukaryotic and prokaryotic)
  • Wide expertise in protein science and molecular biology.
  • Familiarity and/or previous exposure to high throughput and/or large-scale protein production and purification workflows in a pharmaceutical/Biotech environment.
  • Additional experience in mRNA-based vaccine and/or cell engineering is an asset.
  • Understand & implement processes/procedures/policies specific to the vaccine R&D and to GSK with minimal bureaucracy and a focus on efficiency and quality.
  • Fluent in English, oral and writing. Proficiency in French would be highly advantageous.
  • Good communication skills, oral and writing
  • Ability to present scientific data in front of large audience.
  • Good project scientific/technical strategy skills

Preferred Qualifications:If you have the following characteristics, it would be a plus:

  • Demonstrated ability to lead a research or development project within the area of expertise.
  • Experience in managing scientific team(s)
  • Capability to lead projects and implement strategies within a complex matrix organization.

If you have a disability and require assistance during the course of the selection process, you will have the opportunity to let us know what specific assistance you require in order to make suitable arrangements.Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK’s commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Expected salary

Location

Rixensart, Waals Brabant

Job date

Sat, 05 Oct 2024 22:13:49 GMT

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