Principal Scientist Oral Peptide Development

Job title:

Principal Scientist Oral Peptide Development

Company

Johnson & Johnson

Job description

Johnson & Johnson is currently seeking a Principal Scientist, Oral Peptide Development to join our Oral Solid Development department located in Beerse, Antwerp, Belgium.About Johnson & JohnsonAt Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more atAbout the DepartmentThe Global Pharmaceutical Product Development and Supply (PPDS) organization, part of the Discovery, Product Development and Supply (DPDS) division of JJIM, is dedicated to developing advanced drug delivery solutions. Within PPDS, i n the Oral Solid Development department we are looking for an enthusiastic and dedicated colleague who shares our ambition to develop break-through products based on orally available versions of peptides, proteins, oligonucleotides, and other modalities currently delivered via parenteral injection.We are currently seeking a Principal Scientist for Oral Peptide Development at our Beerse site in Antwerp, Belgium. In this pivotal role, you will design and develop novel oral drug delivery systems, scout and evaluate the external innovative solutions and support ongoing collaborations.Key Responsibilities:

• Foster strong collaboration and networking within global teams.
• Enhance and ensure scientific expertise in oral peptide development focusing on oral solid dosage forms and drug delivery systems.
• Drive innovation with a strong focus on customer needs and teamwork.
• Develop formulation strategies and processes that align with JJIM’s commercial capabilities, particularly concentrating on transforming small peptides into effective oral solid dosage forms.

Join our team and contribute to the development of innovative therapeutics that can significantly improve patient outcomes worldwide.Your Impact:As a key member of our PPDS development team, you will significantly influence the future of drug formulation and process development. Your role will entail a wide array of responsibilities, including:

• Contributing to the Formulation Development: Support and drive the formulation of small peptides into oral solid dosage forms.
• Strengthening Stakeholder Relationships: Build and maintain robust relationships with cross-functional stakeholders, collaborating with various departments such as Discovery Pharmaceutics, Preclinical and Clinical, Biopharmaceutical Sciences, Analytical Development, API Development, Clinical Supply Chain, and Regulatory.
• Driving Innovation: Optimize existing formulation and technology platforms, using your expertise to develop novel therapeutic solutions. Identify and screen external innovations in drug delivery specifically tailored for oral peptide delivery into solid dosage forms.
• Collaborative Execution: Work closely with fellow scientists to design, plan, and carry out formulation development activities across our diverse product portfolio.
• Scientific Documentation: Diligently document scientific data and progress, contributing to regulatory submissions, scientific publications, intellectual property initiatives, and strategic decision-making.
• Regulatory, Quality and Safety Compliance: Ensure adherence to regulatory standards, Good Manufacturing Practices (GMP), and performance-based occupational exposure levels.

QualificationsQualificationsWe are looking for a dynamic individual with a robust background in drug product formulation development, specifically focused on oral small peptides. The ideal candidate will possess the following qualifications and attributes:

• Educational Background: A Ph.D. in Pharmaceutical Sciences, Industrial Pharmacy, Biochemical Engineering, Chemical Engineering, Biological or Physical Sciences, or a related field, with at least 5 years of relevant industry and/or academic experience. Alternatively, a Bachelors or Masters Degree in relevant fields with a minimum of 10 years of relevant experience.
• Formulation Expertise: Demonstrated proficiency in formulation design and process development for small peptides into oral solid dosage forms. Familiar with opportunities to enhance permeability of the small peptides in the intestine, as well as experience with targeted or local delivery is a distinct advantage.
• Pre-Formulation and Characterization Knowledge: Familiarity with pre-formulation activities and physico-chemical characterization of Active Pharmaceutical Ingredients (APIs) and final drug products.
• Biopharmaceutical background: Familiarity with the in vitro and in vivo performance of small peptides administered orally, coupled with a basic knowledge of biopharmaceutical principles specific to oral small peptides, would be valuable assets for this position as well.
• Technological Implementation: Expertise in implementing advanced technologies related to drug formulation and development, with the ability to determine critical quality attributes, process parameters, and material attributes.
• Willingness to Travel: A readiness to engage in international travel, approximately 5-15% of the time.

If you are passionate about advancing the field of oral peptide development and possess the qualifications outlined, we encourage you to join our team and make a meaningful impact in pharmaceutical innovation!Join us to make a meaningful impact in the field of pharmaceutical innovation while advancing your career in a supportive and engaging workplace!Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com.

Expected salary

Location

Beerse, Antwerpen

Job date

Sat, 08 Feb 2025 04:59:33 GMT

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