Postdoctoral Researcher: Cancer Metabolism at Single Cell Level

Job title:

Postdoctoral Researcher: Cancer Metabolism at Single Cell Level

Company

VIB

Job description

Overview
The Laboratory for Cellular Metabolism and Metabolic Regulation (Fendt Lab) is a young and dynamic team of researchers performing cutting edge cancer metabolism research with special focus on cancer metastasis and novel metabolic pathways. We exploit mouse models, genetic engineering, metabolomics and single cell & spatial multi-omics analysis to gain groundbreaking insights into metabolism as a driving force of cancer progression. Our work is published in high profile journals such as Nature, Nature Cancer, Cell Reports, and Molecular Cell. We have a strong international recognition and top collaboration partners all over the world.
The VIB-KU Leuven Center for Cancer Biology (CCB), located on Campus Gasthuisberg of the University of Leuven, contributes to the better understanding of the biology that underlies cancer initiation, progression and metastatic dissemination with the ultimate goal to develop more effective and specific anti-cancer (combination) therapies. CCB is currently composed of more than 200 scientists in 14 independent research groups and units. Our scientific interest lies in various hallmarks of tumors and their microenvironment, including inflammation, metabolism, genetic and epigenetic regulating circuits. CCB fosters an interdisciplinary environment and close collaboration with the Comprehensive Cancer Center LKI and the University Hospital, both located on the same campus, to promote translational research.
VIB is an entrepreneurial and vibrant non-profit research institute in Flanders-Belgium with a clear focus on groundbreaking research in life sciences. About 1500 scientists and technologists from over 60 countries are based at the 5 Flemish Universities of Ghent, Leuven, Antwerp, Brussels and Hasselt, and are studying the broad spectrum of molecular mechanisms that regulate the functions of the human body, plants and micro-organisms. Your profile
Are you interested in studying the heterogeneity of metabolism in cancer metastases at a single cell level? You have a strong background (PhD) in single cell/spatial omics technologies and implementation. Having successfully applied state-of-the-art genetic engineering technologies (such as CRISPR/Cas9, lineage tracing), molecular biology techniques including but not limited to western blot, qPCR, FACS, immunohistochemistry (IHC), confocal microscopy and cell culture techniques is a plus. You are interested in metabolism, tumor heterogeneity and metastasis research. You like taking the scientific and experimental lead on a challenging project. You can work independently but also like to collaborate within the team and other research groups. You aim for high impact and are highly ambitious. We offer
Cutting edge research projects
The opportunity to lead exciting research project on metastasis & metabolism
Multidisciplinary and international collaborations
Beyond state-of-the-art technologies including (single cell and spatial) multi-omics analyses
Team work and individual research career development
International team of young and dynamic researchersHow to apply?
Interested candidates should submit their candidacy through the VIB online application tool.
A complete application file (in English and in one single PDF file) should contain the following documents:
motivation letter
full CV
list of publications
contact details of 3 referees
For more information: Please contact us (https://fendtlab.sites.vib.be/… [https://fendtlab.sites.vib.be/en] ) or follow us on Bluesky [https://bsky.app/profile/fendtlab.bsky.social]
ABOUT LEUVENLeuven – only 20 minutes away from Brussels by train – is a vivid university city with a rich history, a well-preserved historical town center and a lively multi-cultural atmosphere. The city is surrounded by charming small villages, woods and nature. Leuven has a lively atmosphere because of the many students from all over the world. Leuven is home to KU Leuven, the largest and oldest university of the Low Countries and the one of the oldest universities in Europe. The related university hospital of UZ Leuven is one of the largest hospitals in Europe. Leuven and the surroundings are a great place for young people and families to live and to raise children. There are many excellent day care centers and schools including an international school.

Expected salary

Location

Leuven, Vlaams Brabant

Job date

Thu, 27 Mar 2025 23:32:49 GMT

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